Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولVariable number tandem repeat polymorphism of the interleukin-1 receptor antagonist gene in meningococcal disease.
Sir—The experience reported by Myoken et al. [1] of superinfection with fungal organisms resistant to itraconazole in patients who are receiving the drug as prophylaxis is of interest. We have not seen superinfections with resistant organisms in immunocompromised HIV-infected patients receiving prophylactic itraconazole. In our experience [2] and in that of others who have reported in vitro tes...
متن کاملIdentifying Variable Number of Tandem Repeat Alleles in Phenylalanine Hydroxylase Gene in Patients with Phenylketonuria in Golestan Province, Iran
Background and Objective: Phenylketonuria (PKU) is a metabolic disorder that is caused by mutations in the phenylalanine hydroxylase (PAH) gene. The multiplicity of mutations in the PAH gene of PKU leads to the cases, in which the pathogenic mutation cannot be detected. In these cases, the variable number of tandem repeat (VNTR), which is the polymorphic marker associated with the PAH gene, is ...
متن کاملVariable number of tandem repeat polymorphisms (VNTRs) in the ACAN gene associated with pectus excavatum.
To the Editor : Pectus excavatum is the most common chest wall deformity, affecting 1 in 400 live births in the United States (1). It occurs commonly in Caucasian males, and is characterized by a depression of the anterior chest wall and sternum resulting in compromised cardiac and respiratory function (2, 3). Genetic factors appear to play a part (4, 5). The CS1 domain of the aggrecan (ACAN) g...
متن کاملMolecular Genetic Analysis of the Variable Number of Tandem-Repeat Alleles at the Phenylalanine Hydroxylase Gene in Iranian Azeri Turkish Population
Background: The variable numbers of tandem-repeat (VNTR) alleles at the phenylalanine hydroxylase (PAH) gene have been used in carrier detection and prenatal diagnosis in phenylketonuria families. This study was carried out to analyze VNTR alleles at the PAH gene in Iranian Azeri Turkish population. Methods: In this study, 200 alleles from general population were studied by PCR. Results: The fr...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2019
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/nlz116